Anti-inflammatory pharmaceutical formulations
AssigneeNorton Healthcare Limited
InventorsAusten John Woolfe, Gordon McIntyre, Nitin Vadilal Sheth
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Abstract
A pharmaceutical dosage form comprising a tablet containing a non-steroidal anti inflammatory drug and misoprostol, wherein the non-steroidal anti inflammatory drug is in the form of coated pellets.
Claims28
A pharmaceutical dosage form comprising a tablet comprising a non-steroidal anti inflammatory drug, misoprostol and an excipient to facilitate dissolution of the misoprostol before dissolution of the non-steroidal anti inflammatory drug, wherein the non-steroidal anti inflammatory drug is in the form of coated pellets.
A method of manufacture of a pharmaceutical tablet comprising the steps of mixing a coated pellet containing a non-steroidal anti inflammatory drug together with a powder containing misoprostol absorbed on a cellulose, polyvinylchloride or other excipient optionally together with one or more binding agents, bulking agents, disintegrants and lubricants and compressing the mixture to form tablets.
A method of manufacture of a pharmaceutical bilayer tablet consisting of mixing, coated pellets containing a non-steroidal anti inflammatory drug with optional excipients selected from binders, bulking agents, disintegrants and lubricants;
- compressing the mixture to form the bottom half of a tablet and superimposing a mixture of misoprostol absorbed on a cellulose or polyvinylchloride or other material together with or more optional excipients selected from binders, bulking agents, disintegrants and lubricants;
- to form a tablet suitable for human administration.
Dependencies are inferred from the claim text.