Colon selective drug delivery composition
AssigneeSamyang Corporation
InventorsSeung-Seo Lee, Sung-Bum La, Chang-Baeg Lim, Sujung Lee, Bo-Youn Seo, Chaul-Min Pai
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Abstract
A composition comprising gelatin and a polysaccharide which is degradable by a colonic enzyme and, optionally, with an aldehyde and/or a polyvalent metal ion and/or an additional polysaccharide, which is not degraded or disintegrated in the upper gastrointestinal tract, thereby rendering the active substance loaded therein to be selectively delivered to the colon and to be effectively released in the colon.
Claims13
A colon selective drug delivery composition comprising a pharmaceutical matrix of a complex of gelatin and an anionic polysaccharide which is degradable by a colonic enzyme.
A colon selective pharmaceutical composition which comprises a colon selective drug delivery composition comprising a pharmaceutical matrix of a complex of gelatin and an anionic polysaccharide which is degradable by a colonic enzyme, and one or more biologically active substances.
Dependencies are inferred from the claim text.