Methods for activating an erythropoietin receptor using antibodies
AssigneeAmgen Inc.
InventorSteven G. Elliott
Life of this patent
Estimating the term…
Abstract
Antibodies and fragments thereof which activate an erythropoietin receptor and stimulate erythropoiesis are described. Also described are hybridoma cell lines which produce the antibodies and methods and compositions for the treatment of anemia.
Claims13
A method of activating an endogenous activity of an erythropoietin receptor in a mammal comprising administering an amount of an antibody or fragment thereof effective to activate the receptor, wherein the antibody or fragment thereof interacts with a peptide consisting of an amino acid sequence as set forth in SEQ ID NO:
- 7.
A method of treating anemia in a patient comprising administering a therapeutically effective amount of an antibody or fragment thereof, wherein the antibody or fragment thereof activates an erythropoietin receptor, and wherein the antibody or fragment thereof interacts with a peptide consisting of an amino acid sequence as set forth in SEQ ID NO:
- 7.
Dependencies are inferred from the claim text.