Method for treatment of bacterial infections with once or twice-weekly administered rifalazil
AssigneeKaneka Corporation
InventorsLynn M. Rose, David J. Porubek, Alan B. Montgomery
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Abstract
A method for treatment of bacterial infections with rifalazil administered once-weekly or twice-weekly. A method for treatment of tuberculosis caused by Mycobacterium tuberculosis, infections caused by Mycobacterium avium complex, infections caused by Chlamydia pneumoniae and infections caused by Helicobacter pylori by administering to a patient suffering from the bacterial infection 1-100 mg of rifalazil once or twice a week. In this dose regimen, the treatment is fast, efficacious and eliminates undesirable secondary symptoms observed with daily doses of 1-50 mg of rifalazil.
Claims16
A method for treatment of bacterial infections caused by Mycobacterium tuberculosis, Mycobacterium avium complex, Chlamydia pneumoniae or Helicobacter pylori in human subjects by once-a-week or twice-a-week administration of rifalazil in a dosage from about 1 to about 100 mg.
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