US 6,310,209 B1Granted

Synthesis of CC-1065/duocarmycin analogs

AssigneeThe Scripps Research Institute

InventorDale L. Boger

Life of this patent

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The present invention relates to a method for the synthesis of the dihydroindole C-ring found in CC-1065/duocarmycin analogs.

Dependent claims

A compound represented by the following structure:

Dependencies are inferred from the claim text.

C07D 471/04
In which the condensed system contains two hetero rings: ortho-condensed systems
C07C 271/28
With the nitrogen atom of at least one of the carbamate groups bound to a carbon atom of a six-membered aromatic ring: to a carbon atom of a…
C07D 209/08
Indoles; Hydrogenated indoles: with only hydrogen atoms or radicals containing only hydrogen and carbon atoms, directly attached to carbon atoms…
C07D 215/54
Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen: attached in position 3

From the US filing history. Foreign family members aren’t listed.

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