Carboxyl-modified superabsorbent protein hydrogel
AssigneeWisconsin Alumni Research Foundation
InventorSrinivasan Damodaran
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Abstract
The present invention is a biodegradable, reversibly-swellable, polyvalent cation-binding, protein hydrogel which comprises an acylated protein matrix in which the acylated protein matrix is crosslinked with a bifunctional crosslinking reagent, and treated with a polar organic solvent, and a method of making the same.
Claims27
A protein hydrogel comprising an acylated protein matrix, the acylated protein matrix being crosslinked with a bifunctional crosslinking reagent to yield a crosslinked protein matrix, the crosslinked protein matrix then being treated with a polar organic solvent.
A protein hydrogel comprising:
- a fish protein isolate, the fish protein isolate being acylated by treatment with ethylenediaminetetraacetic acid dianhydride to yield an acylated protein;
- the acylated protein being crosslinked with glutaraldehyde to yield a crosslinked protein matrix;
- and
- the crosslinked protein matrix being treated with a polar organic solvent.
A method of making a protein hydrogel, the method comprising the steps of:
- (a) treating a protein with an acylating agent to yield an acylated protein;
- (b) crosslinking the acylated protein with a bifunctional crosslinking agent to yield a crosslinked protein;
- and
- (c) treating the crosslinked protein with a polar organic solvent.
Dependencies are inferred from the claim text.