US 6,310,041 B1Granted

Synthetic complementary peptides and ophthalmologic uses thereof

AssigneeFornix Biosciences N.V.

InventorsJeffrey Lynn Haddox, Roswell Robert Pfister, James Edwin Blalock, Matteo Villain

Life of this patent

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Abstract

The present invention is directed to a series of complementary peptides for the pro-gly-pro sequence as antagonists of polymorphonuclear leukocyte chemoattractants. Also provided are applications of such peptides for treating alkali-injuried eyes and other types of diseases.

Claims7

Dependent claims

A pharmaceutical composition for ophthalmologic uses comprising a complementary peptide having a sequence complementary to proline-glycine-proline (PGP).

Dependencies are inferred from the claim text.

Facts

Application: 09/521,365Filed 8 Mar 2000 · us provisional application
Priority: 9 Mar 1999
Granted: 30 Oct 2001
Term ends: Not estimatedThe source records don’t support an estimate.

Classification9 codes

C07K 7/06
Linear peptides containing only normal peptide links: having 5 to 11 amino acids
C07K 5/0806
And aliphatic: the side chain containing 0 or 1 carbon atoms, i.e. Gly, Ala
C07K 5/0817
With the first amino acid being basic: the first amino acid being Arg
C07K 5/0823
With the first amino acid being heterocyclic, e.g. His, Pro, Trp: and Pro-amino acid; Derivatives thereof

Family

Application60/123,409Us provisional application · filed 9 Mar 1999
US 6,310,041 B1This patent

From the US filing history. Foreign family members aren’t listed.

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