Method of controlling protozoan infections using syringomycin-family lipodepsipeptides
AssigneeUtah State University
InventorsJon Y. Takemoto, John R. Forney, Mark C. Healey, Shiguang Yang, Karl A. Werbovetz
Life of this patent
Estimating the term…
Abstract
A method for controlling infections caused by protozoans, such as Cryptosporidium parvum, Plasmodium falciparum, and Leishmania donovani. The method comprises using syringomycin-family lipodepsipeptides, preferably syringomycins such as syringomycin E, to control or prevent infections caused by protozoans. The method is directed to therapeutic treatment of mammals, such as humans, exposed to protozoans, and additionally as a prophylactic treatment in immunocompromised subjects at high risk for contracting protozoan infections.
Claims16
A method of treating a protozoal infection in a mammal which comprises administering to said mammal a syringomycin lipodepsipeptide in an amount sufficient to interfere with the protozoal infection.
A method of preventing a protozoal infection in a mammal which comprises administering to said mammal a syringomycin lipodepsipeptide in an amount sufficient to prevent the protozoal infection in said mammal.
Dependencies are inferred from the claim text.