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US 6,309,887 B1Granted
Filter paper treatment for improved diagnostic assays
AssigneeFlexSite Diagnostics, Inc.
InventorRobert A. Ray
Life of this patent
Estimating the term…
Abstract
Filter paper absorbed with a solution of anticoagulant, e.g., ethylene diamine tetra-acetic acid (EDTA), then dried, useful for collection of a blood sample for analysis of hemoglobin or a hemoglobin fraction in the sample showed higher precision in standard assays than untreated filter paper. Methods of using the anticoagulant-treated filter paper are also described.
Claims12
A method for assaying a hemoglobin in a liquid biological sample, said method comprising:
- providing a material for absorbing the biological sample comprising the hemoglobin, the material containing a chelating agent for preventing the liquid biological sample from coagulating;
- applying the liquid biological sample to the chelating agent-containing material;
- allowing the liquid biological sample to dry into a dried biological sample on the material;
- eluting the dried biological sample from the material, whereby tile chelating agent facilitates elution of the dried biological sample from the material to improve the precision of the method;
- and
- assaying the hemoglobin in the eluted dried biological sample.
3 more elements
The method 7, wherein the glycohemoglobin is HbA1c.
Dependencies are inferred from the claim text.