Process for producing foreign proteins
AssigneeYoshitomi Pharmaceutical Industries, Ltd.
InventorsToyoo Ohda, Tomoshi Ohya, Shinobu Kuwae, Masao Ohyama, Kaoru Kobayashi, Yahiro Uemura
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Abstract
A production method of a heterologous protein, comprising culturing a heterologous protein-producing host prepared by gene manipulation in a medium containing a fatty acid or a salt thereof, and a surfactant and harvesting the heterologous protein from the culture. The production amount of the heterologous protein produced by a heterologous protein-producing host can be increased. Moreover, since decomposition of the heterologous protein by an enzyme derived from the host can be inhibited, enabling large scale production of a heterologous protein.
Claims4
A production method of human serum albumin, comprising culturing a human serum albumin-producing microbial host prepared by gene manipulation in a medium containing a fatty acid having 10 to 26 carbon atoms or a salt thereof, and a surfactant and harvesting the human serum albumin from the culture.
Dependencies are inferred from the claim text.