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US 6,309,640 B1Granted
Lipoprotein lipase suppression by endotoxin-induced mediator (shock assay)
AssigneeThe Rockefeller University
InventorsAnthony Cerami, Masanobu Kawakami
Life of this patent
Estimating the term…
Abstract
Pharmaceutical compositions are provided which comprise neutralizing antibodies to the about 70 kDa mediator produced upon invasive stimulation of macrophages by, e.g., contact with endotoxin.
Claims2
A pharmaceutical composition comprising an effective amount of a neutralizing antibody to the about 70 kDa mediator substance which results from endotoxin stimulation of macrophages and which has the biological activity of suppression of lipoprotein lipase activity and a pharmaceutically active diluent, adjuvant or carrier.
Dependencies are inferred from the claim text.