Back to results
US 6,309,637 B1Granted
Human microfibril-associated glycoprotein 4 splice variant
AssigneeIncyte Genomics, Inc.
InventorsY. Tom Tang, Neil C. Corley, Purvi Shah
Life of this patent
Estimating the term…
Abstract
The invention provides a human microfibril-associated glycoprotein 4 splice variant (MAG4V) and polynucleotides which identify and encode MAG4V. The invention also provides expression vectors, host cells, antibodies, agonists, and antagonists. The invention also provides methods for treating or preventing disorders associated with expression of MAG4V.
Claims13
An isolated antibody which specifically binds to a polypeptide comprising an amino acid sequence selected from the group consisting of:
- a) an amino acid sequence of SEQ ID NO:1,
- b) a naturally-occurring amino acid sequence having at least 95% sequence identity to the sequence of SEQ ID NO:1, wherein said naturally-occurrng amino acid sequence has the ability to support proliferation of fibroblasts or tumor cells under serum-free conditions and
- c) an immunogenic fragment of the region from amino acid residues 1 through 27 of SEQ ID NO:1 .
Dependencies are inferred from the claim text.