Post-blending valve degasser
AssigneeSystec, Inc.
InventorsCarl W. Sims, Yuri Gerner, Thomas J. Thielen
Life of this patent
Estimating the term…
Abstract
A flow-through vacuum degassing unit for degassing a mobile phase includes a vacuum conduit adapted to be connected to a source for creating a vacuum in the conduit, an inlet port and an outlet port for admitting and discharging the mobile phase to be degassed, a degassing tube for conducting the mobile phase through the conduit, wherein the degassing tube is a gas-permeable, liquid impermeable material. In a particular embodiment, the degassing tube receives multiple mobile phases blended together in a discrete volume of desired composition.
Claims18
A method of degassing one or more liquids in a flow-through vacuum apparatus comprising:
- a) providing one or more distinct mobile phases for transport in a gas-permeable, liquid-impermeable degassing tube, said degassing tube being at least partially disposed in a sealed conduit, which conduit is adapted to be connected to a vacuum source for evacuating the conduit;
- b) providing a pump means for drawing the one or more mobile phases through the degassing tube;
- c) providing a liquid blending means for mixing said one or more distinct mobile phases into a single blended mobile phase stream;
- and
- d) positioning said degassing tube downstream from said blending means, and between said blending means and said pump means.
A flow-through vacuum degassing apparatus comprising:
- a conduit forming a chamber and adapted to be connected to a vacuum source for creating a vacuum within the conduit;
- an inlet port forming an inlet connection and an outlet port forming an outlet connection for receiving and discharging a fluid to be degassed, said inlet connection and said outlet connection each including coupling means for fluidly interconnecting respective components in a liquid chromatography system;
- and
- a gas-permeable, liquid-impermeable tube for conducting the fluid through the conduit, said tube being operably connected between the inlet port and the outlet port for providing a degassing means disposed downstream from a fluid blending chamber component of said liquid chromatography system, which blending chamber operably mixes discrete fluids to form a chromatographic mobile phase.
A flow-through vacuum degassing apparatus for use in degassing a liquid in a liquid chromatography system, comprising:
- a vacuum duct adapted to be connected to a source for creating a vacuum in the duct;
- a liquid inlet port and a liquid outlet port, said inlet port and said outlet port forming respective inlet and outlet connections, said inlet and outlet connections each including coupling means for interconnecting respective chromatographic components;
- and
- a degassing tube for conducting the liquid through the vacuum duct, said tube being connected to said inlet connection and said outlet connection, said tube being formed of a gas-permeable, liquid-impermeable material, said tube being operably disposed downstream from a liquid blending chamber so as to receive and degas multiple liquids blended together such that the blended liquid passing through the outlet port is suitably degassed for use as a mobile phase in said liquid chromatography system.
Dependencies are inferred from the claim text.