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US 6,307,074 B1Granted
Process for the preparation of bile acid derivatives
AssigneeBracco Internatinal B.V.
InventorsMarino Brocchetta, Chiara Gallotti, Massimo Visigalli, Pier Lucio Anelli
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Abstract
A process for the preparation of the compounds of general formula (I) in which R1 is H or OH; R2 is H, α-OH, or β-OH; and R3 is a straight or branched C1-C4 alkyl group or a benzyl group, comprising the reduction of compounds of formula (III) wherein R1, R2 and R3 have the same meanings as in formula I, in the presence of sodium borohydride.
Claims11
A process for the preparation of compounds of general formula (I)
- in which
- R1 is H or OH;
- R2 is H, α-OH, or β-OH;
- and
- R3 is a straight or branched C1-C4 alkyl group, or a benzyl group;
- comprising the reduction of compounds of general formula (III)
- wherein R, R2 and R3 have the same meanings as in formula (I), in the presence of sodium borohydride.
4 more elements
Dependencies are inferred from the claim text.