Stable aqueous formulation of 3-(N-butylacetamino)-propionic acid ethyl ester
AssigneeMerck Patent GmbH
InventorsThekla Kurz, Sabine Hitzel, Dorothee Wille, Mohammad Jalalian
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Abstract
The present invention relates to stable aqueous formulations of the insect repellent ethyl 3-(N-butyl-acetamino)propionate.
Claims11
A stable aqueous formulation of the insect repellent ethyl 3-(N-butylacetamino) propionate, comprising ethyl 3-(N-butylacetamino) propionate in a buffered solution or buffer system having a pH of 3.5 or greater, selected from a group consisting of citric acid/Na2HPO4, tris(hydroxymethyl) amino-methane/HCl, disodium citrate/HCl, potassium hydrogen-phthalate/NaOH, disodium citrate/NaOH, potassium dihydrogenphosphate/disodium hydrogenphosphate, and triethanolamine and Titriplex III/HCl.
A method of repelling insects, comprising applying to a subject a stable aqueous formulation of an insect repellent containing ethyl 3-(N-butylacetamino) propionate, which is buffered at a pH at least 3.5 by a buffer system, wherein said buffer system is citric acid/Na2HPO4, tris(hydroxymethyl) aminomethane/HCl, disodium citrate/HCl, potassium hydrogenphosphate or triethanolamine and Titriplex III/HCl.
Dependencies are inferred from the claim text.