Oxaliplatin formulations
AssigneeSanofi-Synthelabo
InventorsNicholas H. Anderson, Ross Blundell, Stephen Brown, David A. England, Martin R. Gray
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Abstract
The invention relates to pharmaceutically stable oxaliplatin solution formulations, to the method of use thereof in the treatment of cancer tumors, to processes for the preparation of such formulations, and to a method for stabilizing solutions of oxaliplatin.
Claims24
A stable oxaliplatin solution formulation comprising a therapeutically effective amount of oxaliplatin, an effective stabilizing amount of a buffering agent and a pharmaceutically acceptable carrier wherein the buffering agent is oxalic acid or an alkali metal salt thereof.
A method for stabilizing a solution comprising a therapeutically effective amount of oxaliplatin which comprises adding an effective stabilizing amount of a buffering agent to said solution wherein the buffering agent is oxalic acid or an alkali metal salt thereof.
Dependencies are inferred from the claim text.