US 6,306,889 B1Granted

Compounds, methods and pharmaceutical compositions for treating neural or cardiovascular tissue damage

AssigneeGuilford Pharmaceuticals Inc.

InventorsJia-He Li, Jie Zhang, Paul F. Jackson, Keith M. Maclin

Life of this patent

Estimating the term…

Abstract

This invention relates to compounds, pharmaceutical compositions, and methods for the treatment or prevention of neural or cardiovascular tissue damage related to cerebral ischemia and reperfusion injury in an animal by administering Poly(ADP-ribose) polymerase (“PARP”) inhibitors.

Claims10

Dependent claims

The compound of the formula:

Dependencies are inferred from the claim text.

Facts

Application: 09/047,502Filed 25 Mar 1998 · continuation in part
Priority: 3 Sep 1997
Granted: 23 Oct 2001
Term ends: Not estimatedThe source records don’t support an estimate.

Classification11 codes

C07D 249/08
Not condensed with other rings: 1,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
A61K 31/4741
Ortho- or peri-condensed with heterocyclic ring systems: condensed with ring systems having oxygen as a ring hetero atom, e.g. tubocuraran…
A61K 31/502
Pyridazines; Hydrogenated pyridazines: ortho- or peri-condensed with carbocyclic ring systems, e.g. cinnoline, phthalazine
A61K 31/5025
Pyridazines; Hydrogenated pyridazines: ortho- or peri-condensed with heterocyclic ring systems

Family

Application08/922,548Parent of this continuation-in-part · filed 3 Sep 1997
US 6,346,536 B1Related patent
US 6,306,889 B1This patent

From the US filing history. Foreign family members aren’t listed.

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