Triazole antifungal agent
AssigneeSankyo Company, Limited
InventorsSadao Oida, Teruo Tanaka, Yawara Tajima, Toshiyuki Konosu, Atsushi Somada, Takeo Miyaoka, Hiroshi Yasuda
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AssigneeSankyo Company, Limited
InventorsSadao Oida, Teruo Tanaka, Yawara Tajima, Toshiyuki Konosu, Atsushi Somada, Takeo Miyaoka, Hiroshi Yasuda
Estimating the term…
A triazole compound having the formula: wherein Ar1 represents a phenyl group which may be substituted; Ar2 represents a phenyl group which may be substituted; R0 represents a hydrogen atom or a lower alkyl; R1 represents a lower alkyl; R2 to R5 each represnet a hydrogen atom or an unsubstituted or halo substituted alkyl; n represnets 0 to 2; p represents 0 or 1; q, r and s each represent 0 to 2; A represents a 4- to 7-membered carbon ring or a 4- to 7-membered heterocyclic, not including 1,3-dioxan-5-yl. The compound of the present invention exhibits an excellent antifungal activity.
A triazole compound having the formula:
The triazole compound or a pharmacologically acceptable salt thereof according to claims 12, or 3, wherein Ar2 represents an unsubstituted phenyl group.
The triazole compound or a pharmacologically acceptable salt thereof according to claims 12, or 3, wherein Ar2 represents a phenyl group having 1 to 3 substituents selected from the group consisting of an unsubstituted lower alkyl group, a halogen atom, a halo substituted lower alkyl group a halo substituted lower alkoxy group, a nitro group, a cyano group or a —S(O)mR6 group, wherein R6 represents an unsubstituted or halo substituted lower alkyl group and m represents 0, 1 or 2.
The triazole compound or a pharmacologically acceptable salt thereof according to claims 12, or 3, wherein Ar2 represents a phenyl group having 1 or 2 substituents selected from the group consisting of an unsubstituted lower alkyl group, a halogen atom, a halo substituted lower alkyl group, a halo substituted lower alkoxy group, a nitro group, a cyano group or a -S(O)mR6 group, wherein R6 represents an unsubstituted or halo substituted lower alkyl group and m represents 0, 1 or 2.
Dependencies are inferred from the claim text.