Zwitterionic fatty acid compounds for anti-inflammation
OwnerPeter T. Pugliese, Peter M. Puglieseinventors
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Abstract
Methods for treating muscular inflammation comprise applying to an inflamed area a therapeutically effective amount of a skin-compatible ester of a zwitterionic aminosulphonic acid of the formula wherein M is an alkali metal and R is a straight chain aliphatic acid moiety. Compositions for treating inflammation comprising a therapeutically effective amount of a skin-compatible component comprising an ester, ether, urethane, amide or urea of at least one compound selected from a specified group. Additional methods for treating inflammation comprise applying to an inflamed area a therapeutically effective amount of a skin-compatible component comprising an ester, ether, urethane, amide or urea of at least one compound selected from a specified group.
Claims15
A method for treating muscular inflammation, comprising applying to an inflamed area a therapeutically effective amount of a skin-compatible ester of a zwitterionic aminosulphonic acid of the formula
- wherein M is an alkali metal and R is a straight chain aliphatic acid moiety.
A method for treating inflammation, comprising applying to an inflamed area a therapeutically effective amount of a skin-compatible component comprising an ester, ether, urethane, amide or urea of at least one compound selected from the group consisting of
- N-(2-acetamido)-2-aminoethane sulfonic acid (ACES),
- 3-[1,1-dimethyl-2-hydroxyethyl amino]-2-hydroxypropane sulfonic acid (AMPSO),
- N,N-bis (hydroxyethyl)-2-aminoethane sulfonic acid (BES),
- 3-[N,N-bis (hydroxyethyl) amino]-2-hydroxypropane sulfonic acid (DIPSO),
- 3-(cyclohexylamino)-1-propane sulfonic acid (CAPS),
- 3-(cyclohexylamino)-1-hydroxypropane sulfonic acid (CAPSO),
- 2-(N-cyclohexylamino) ethane sulfonic acid (CHES),
- N-(2-hydroxyethyl) piperazine-N′-3-propane sulfonic acid (HEPPS),
- N-(2-hydroxyethyl) piperazine-N′-2-hydroxypropane sulfonic acid (HEPPSO),
- 2-(N-morpholino) ethane sulfonic acid (MES),
- 3-(N-morpholino) propane sulfonic acid (MOPS),
- 3-(N-morpholino)-2-hydroxypropane sulfonic acid (MOPSO),
- piperazine-N,N′-bis (2-ethane sulfonic acid) (PIPES),
- piperazine-N′-(2-ethane sulfonic acid) (mono PIPES),
- piperazine-N,N′-bis (2-hydroxypropane sulfonic acid) (POPES),
- 3-[N-tris-(hydroxymethyl) methyl amine]-2-hydroxypropane sulfonic acid (TAPS), and
- N-tris-(hydroxymethyl) methyl-2-amine ethane sulfonic acid (TES).
A composition for treating inflammation, comprising a therapeutically effective amount of a skin-compatible component comprising an ester, ether, urethane, amide or urea of at least one compound selected from the group consisting of
- N-(2-acetamido)-2-aminoethane sulfonic acid (ACES),
- 3-[1,1-dimethyl-2-hydroxyethyl amino]-2-hydroxypropane sulfonic acid (AMPSO),
- N,N-bis (hydroxyethyl)-2-aminoethane sulfonic acid (BES),
- 3-[N,N-bis (hydroxyethyl) amino]-2-hydroxypropane sulfonic acid (DIPSO),
- 3-(cyclohexylamino)-1-propane sulfonic acid (CAPS),
- 3-(cyclohexylamino)-1-hydroxypropane sulfonic acid (CAPSO),
- 2-(N-cyclohexylamino) ethane sulfonic acid (CHES),
- N-(2-hydroxyethyl) piperazine-N′-3-propane sulfonic acid (HEPPS),
- N-(2-hydroxyethyl) piperazine-N′-2-hydroxypropane sulfonic acid (HEPPSO),
- 2-(N-morpholino) ethane sulfonic acid (MES),
- 3-(N-morpholino) propane sulfonic acid (MOPS),
- 3-(N-morpholino)-2-hydroxypropane sulfonic acid (MOPSO),
- piperazine-N,N′-bis (2-ethane sulfonic acid) (PIPES),
- piperazine-N′-(2-ethane sulfonic acid) (mono PIPES),
- piperazine-N,N′-bis (2-hydroxypropane sulfonic acid) (POPES),
- 3-[N-tris-(hydroxymethyl) methyl amine]-2-hydroxypropane sulfonic acid (TAPS), and
- N-tris-(hydroxymethyl) methyl-2-amine ethane sulfonic acid (TES).
Dependencies are inferred from the claim text.