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AssigneeSenju Pharmaceutical Co., Ltd.
InventorShirou Sawa
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The present invention relates to a method for solubilizing pyridonecarboxylic acid or a pharmacologically acceptable salt thereof, which includes incorporating glycyrrhizic acid or a salt thereof and pyridonecarboxylic acid or a pharmacologically acceptable salt thereof, a solubilizer therefor, an aqueous solution containing the solubilized pyridonecarboxylic acid or a pharmacologically acceptable salt thereof, and a method of producing the aqueous solution. According to the solubilizing method of the present invention, the solubility of pyridonecarboxylic acid compound and salts thereof near physiological pH can be increased. Therefore, these compounds can be prepared into an aqueous solution to be applied as an eye drop, a nasal drop and an ear drop.
A method for solubilizing pyridonecarboxylic acid or a pharmacologically acceptable salt thereof, comprising incorporating glycyrrhizic acid or a salt thereof and pyridonecarboxylic acid or a pharmacologically acceptable salt thereof.
An aqueous solution comprising pyridonecarboxylic acid or a pharmacologically acceptable salt thereof, and glycyrrhizic acid or a salt thereof.
A method for producing an aqueous solution comprising pyridonecarboxylic acid or a pharmacologically acceptable salt thereof, which comprises incorporating glycyrrhizic acid or a salt thereof and pyridonecarboxylic acid or a pharmacologically acceptable salt thereof.
Dependencies are inferred from the claim text.