Method for preventing and/or treating renal disease
AssigneeSnow Brand Milk Products Co., Ltd.
InventorsMasahiko Kinosaki, Hiromi Ogawa, Hiroaki Masunaga, Fumie Kobayashi, Kyoji Yamaguchi, Kanji Higashio
Life of this patent
Estimating the term…
Abstract
A preventative and/or therapeutic agent to treat and/or prevent organ failure due to mercury exposure, contains as the active ingredient a mutant tumor cytotoxic factor protein (TCF-II). The therapeutic agent comprises a mutant TCF-II protein according to SEQ ID NO. 2 in which amino acid residues Arg-Lys-Arg-Arg have been replaced by Ala-Ala-Ala-Ala, or in which amino acids Lys-Ile-Lys-Thr-Lys-Lys have been replaced by Ala-Ile-Ala-Thr-Ala-Ala (SEQ ID NO. 3).
Claims5
A method of treating renal failure due to mercury exposure, comprising:
- administering to a patient who has been exposed to mercury, an effective amount of a pharmaceutical preparation comprising a mutant TCF-II protein according to SEQ ID NO. 2 in which amino acid residues Arg-Lys-Arg-Arg have been replaced by Ala-Ala-Ala-Ala, or a pharmacologically acceptable salt thereof.
A method of treating renal failure due to mercury exposure, comprising:
- administering to a patient who has been exposed to mercury, an effective amount of a pharmaceutical preparation comprising a mutant TCF-II protein according to SEQ ID NO. 3 in which amino acid residues Lys-Ile-Lys-Thre-Lys-Lys have been replaced by Ala-Ile-Ala-Thre-Ala-Ala, or a pharmaceutical salt thereof.
Dependencies are inferred from the claim text.