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US 6,306,632 B1Granted
Chromatin associated proteins
AssigneeE. I. Du Pont de Nemours and Company
InventorsRebecca E. Cahoon, J. Antoni Rafalski
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Abstract
This invention relates to an isolated nucleic acid fragment encoding a chromatin associated protein. The invention also relates to the construction of a chimeric gene encoding all or a portion of the chromatin associated protein, in sense or antisense orientation, wherein expression of the chimeric gene results in production of altered levels of the chromatin associated protein in a transformed host cell.
Claims31
An isolated polynucleotide comprising:
- (a) a nucleotide sequence encoding a polypeptide having lamin B receptor/sterol reductase activity, wherein the amino acid sequence of the polypeptide and the amino acid sequence of SEQ ID NO:2 or SEQ ID NO:4 have at least 80% identity based on the Clustal alignment method, or
- (b) the complement of the nucleotide sequence of (a).
An isolated polynucleotide comprising:
- (a) a nucleotide sequence encoding a polypeptide having lamin B receptor/sterol reductase activity, wherein the amino acid sequence of the polypeptide and the amino acid sequence of SEQ ID NO:6 have at least 90% identity based on the Clustal alignment method, or
- (b) the complement of the nucleotide sequence of (a).
Dependencies are inferred from the claim text.