Aspergillus porphobilinogen synthases and nucleic acids encoding same
AssigneeNovozymes Biotech, Inc.
InventorsAubrey Jones, Joel R. Cherry
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Abstract
The present invention relates to Aspergillus porphobilinogen synthases and isolated nucleic acid fragments comprising nucleic acid sequences encoding the porphobilinogen synthases as well as nucleic acid constructs, vectors, and recombinant host cells comprising the nucleic acid sequences. The invention also relates to methods of producing the porphobilinogen synthases.
Claims24
An isolated nucleic acid sequence encoding a porphobilinogen synthase, wherein the nucleic acid sequence (a) encodes a porphobilinogen synthase having an amino acid sequence which has at least 90% identity with amino acids 1 to 375 of SEQ ID NO:2, or (b) hybridizes under high stringency conditions with nucleotides 383 to 1553 of SEQ ID NO:1, or the cDNA sequence contained in nucleotides 383 to 1553 of SEQ ID NO:1.
Dependencies are inferred from the claim text.