Apomorphine-containing dosage forms for ameliorating male erectile dysfunction
AssigneePentech Pharmaceuticals, Inc.
InventorsRagab El-Rashidy, Bruce Ronsen
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Abstract
Psychogenic impotence can be ameliorated without substantial undesirable side effects by administration of apomorphine and an antiemetic agent in an amount sufficient to substantially reduce nausea symptoms associated with the use of apomorphine.
Claims17
A layered tablet composition for sublingual administration to treat erectile dysfunction, comprising an apomorphine core portion having a first T50 value and an outer layer portion comprising an antiemetic agent having a second T50 value, wherein the first T50 is greater than the second T50, said composition further comprising an osmotic agent, and a swellable hydrophilic carrier.
An antiemetic-apomorphine tablet composition suitable for sublingual delivery to treat erectile dysfunction, comprising:
- a core comprising an apomorphine component having a first T50 value;
- and
- an outer layer comprising an antiemetic agent having a second T50 value, wherein said first T50 is greater than said second T50 value.
Dependencies are inferred from the claim text.