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US 6,306,426 B1Granted
Implant device with a retinoid for improved biocompatibility
AssigneeAllergan Sales, Inc.
InventorsOrest Olejnik, Patrick M. Hughes, John S. Kent
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Abstract
An implant device is provided which incorporates a retinoid for improving the biocompatibility of the device in tissue. The device may be bioerodible for the purpose of systemically or locally releasing a therapeutic agent in tissue or it may be a permanent implant which includes a surface treated with a retinoid for increasing the biocompatibility thereof.
Claims10
An implantable device for providing systemic or local release of a therapeutic agent in tissue, the device comprising:
- a therapeutic agent;
- a carrier sized for insertion into tissue in which systemic release of the therapeutic agent is desired, said carrier including means for providing controlled release of the therapeutic agent wherein said means comprises a biodegradable polymer;
- and
- a retinoid, separate from the therapeutic agent and homogeneously distributed throughout the device for improving biocompatibility of said device in said tissue.
1 more element
Dependencies are inferred from the claim text.