Medical uses of styrene sulfonate polymers
AssigneeAegis Biosciences, LLC
InventorsDavid Vachon, Gary E. Wnek
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Abstract
Wound dressings and coated implantable medical devices include a styrene sulfonate polymer. Organic and inorganic therapeutic agents may be incorporated in the copolymer. Inorganic therapeutic agents are oligodynamic metals, especially silver.
Claims33
A wound dressing for covering a wound, said wound dressing comprising at least one layer having al least one surface contactable with the wound and having disposed thereon a styrene sulfonate copolymer having a molecular weight of at least 20,000 and comprising:
- residues derived from at least one olefin comonomer;
- and
- 20-80% by weight residues derived from styrene and comprising at least 15 mole percent styrene sulfonate structural units of formula I:
- wherein A+ is hydrogen ion, ammonium, an ion of an alkali metal, an ion of an oligodynamic metal or the cation of a therapeutic agent.
A wound dressing for covering a skin wound, said wound dressing comprising at least one layer having at least one surface contactable with the skin wound and having disposed thereon a polymer blend comprising a styrene sulfonate copolymer, said styrene sulfonate copolymer comprising residues derived from at least one olefin comonomer and structural units of formula I:
- wherein A+ is hydrogen, ammonium, an alkali metal, an oligodynamic metal or the cation of a therapeutic agent.
A process for the preparation of a hydrogel polymer comprising at least one of silver ion and silver metal, said process comprising:
- combining the hydrogel polymer with aqueous silver ion;
- and
- optionally, at least partly reducing the silver ion to silver metal.
Dependencies are inferred from the claim text.