Controlled expansion sphincter augmentation media

A method for increasing urine flow resistance in a patient having urinary incontinence comprising inserting into tissues surrounding the patient's urethra and into contact with body fluids, a selected volume of a physiologically acceptable composition comprising a plurality of physiologically acceptable solid hydrophilic polymer particles dispersed in a physiologically acceptable biodissipatable liquid carrier, the plurality of solid polymer particles, prior to being positioned in contact with body fluids having a volume which is less than a predetermined volume, hydrating following being positioned in contact with body fluids and on hydration absorbing at least about 30 wt % water based on weight of the solid hydrophilic polymer particles and swelling to assume the predetermined volume and being substantially insoluble in body fluids.

A method for treating a patient having vesicoureteral reflux comprising inserting into tissues adjacent the patient's ureteral orifice and into contact with body fluids, a selected volume of a physiologically acceptable composition comprising a plurality of physiologically acceptable solid hydrophilic polymer particles in a physiologically acceptable biodissipatable liquid carrier, the plurality of solid polymer particles, prior to being positioned in contact with body fluids having a volume which is less than a predetermined volume, hydrating following being positioned in contact with body fluids and on hydration absorbing at least about 30 wt % water based on weight of the solid hydrophilic polymer particles and swelling to assume the predetermined volume and being substantially insoluble in body fluids.

A method of deforming a selected tissue structure comprising inserting into tissues adjacent the selected tissue structure a selected volume of a physiologically acceptable composition comprising a plurality of physiologically acceptable solid polymer particles dispersed in a physiologically acceptable biodissipatable liquid carrier, the plurality of solid polymer particles, prior to being positioned adjacent the selected tissue structure having a volume which is less than a predetermined volume, and swelling, following being positioned adjacent the selected tissue structure, to assume the predetermined volume and being substantially insoluble in body fluids.

A method for increasing urine flow resistance in a patient having urinary incontinence comprising inserting into tissues surrounding the patient's urethra a selected volume of a physiologically acceptable composition comprising a plurality of physiologically acceptable solid polymer particles dispersed in a physiologically acceptable biodissipatable liquid carrier, the plurality of solid polymer particles, prior to being positioned in tissues surrounding the patient's urethra having a volume which is less than a predetermined volume, swelling to assume the predetermined volume following insertion and being substantially insoluble in body fluids.

A method for treating a patient having vesicoureteral reflux comprising inserting into tissues adjacent the patient's ureteral orifice a selected volume of a physiologically acceptable composition comprising a plurality of physiologically acceptable solid polymer particles in a physiologically acceptable biodissipatable liquid carrier, the plurality of solid polymer particles, prior to being positioned adjacent the patient's ureteral orifice having a volume which is less than a predetermined volume and swelling to assume the predetermined volume following insertion and being substantially insoluble in body fluids.

A method of deforming a selected tissue structure comprising inserting into tissues adjacent the selected tissue structue a selected volume of a physiologically acceptable composition comprising a plurality of substantially unswollen physiologically acceptable solid polymer particles dispersed in a physiologically acceptable biodissipatable liquid carrier, the plurality of solid polymer particles, prior to being positioned adjacent the selected tissue structure having a volume which is less than a predetermined volume, and swelling, following being positioned adjacent the selected tissue structure, to assume the predetermined volume and being substantially insoluble in body fluids.

A method for exerting pressure on a selected tissue structure comprising inserting into tissues adjacent the selected tissue structure a selected volume of a physiologically acceptable composition comprising a plurality of physiologically acceptable solid polymer particles which are capable of absorbing water upon being inserted adjacent the selected tissue structure and of, upon absorbing water, swelling and are dispersed in a physiologically acceptable biodissipatable liquid carrier, the plurality of solid polymer particles, prior to being positioned adjacent the selected tissue structure having a volume which is less than a predetermined volume, and swelling, following being positioned adjacent the selected tissue structure, to assume the predetermined volume and being substantially insoluble in body fluids.