Aerosol formulations containing P134a and particulate medicament

A pharmaceutical aerosol formulation consisting essentially of:

• (a) an effective amount of particulate formoterol or a salt thereof as bronchodilatory medicament;
• (b) an effective amount of particulate budesonide as anti-inflammatory medicament;
• and
• (c) 1,1,1,2-tetrafluoroethane as propellant;
• which formulation contains less than 0.0001% surfactant by weight of the medicaments and wherein the particulate medicaments being present in an amount of 0.005% to 5% w/w relative to the total weight of the formulation and having a particle size of less than 100 microns.

A pharmaceutical aerosol formulation consisting of:

• (a) an effective amount of particulate formoterol or a salt thereof as bronchodilatory medicament;
• (b) an effective amount of particulate budesonide as anti-inflammatory medicament;
• and
• (c) 1,1,1,2-tetrafluoroethane as propellant and wherein the particulate medicaments being present in an amount of 0.005% to 5% w/w relative to the total weight of the formulation and having a particle size of less than 100 microns.