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AssigneeAlbert Einstein College of Medicine of Yeshiva University
InventorHerman Buschke
Estimating the term…
This invention relates to a method for increasing the usefulness, sensitivity and specificity of tests that measure memory and facets of memory, including learning, retention, recall and/or recognition. Specifically, the sensitivity and specificity of such tests are enhanced by selectively weighting the value of specific items recalled by the test subject, either by weighting such items within any specific testing trial or across numerous testing trials. Also disclosed are various methods of reducing ceiling effects in memory tests. The invention also provides improved tests which employ item-specific weighting for the diagnosis of Alzheimer's Disease and other dementia characterized by memory impairment, as well as a method of screening for and evaluating the efficacy of potential therapeutics directed to the treatment of such dementia.
A method for measuring memory in a subject, comprising the steps of:
A method for measuring memory in a subject, comprising the steps of:
A method of reducing ceiling effects in serial processing memory tests, comprising introducing an interference delay between (a) presentation of a list of items to a subject wherein said items are to be recalled from memory by the subject and (b) first recall of the items by the subject from memory, wherein each item recalled from memory by the subject is assigned a non-normative weighted value in each trial.
A method of reducing ceiling effects in serial processing memory tests using free and cued recall, comprising scoring the test by selectively weighting the value of each item recalled by the subject in each trial without presentation of a cue, wherein each item recalled from memory by the subject is assigned a non-normative weighted value in each trial.
Dependencies are inferred from the claim text.