Recombinant avian adenovirus vector
AssigneeCommonwealth Scientific and Industrial Research Organisation
InventorsMichael A. Johnson, Christopher T. Prideaux, Richard J. McCoy, John W. Lowenthal
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Abstract
This invention relates to a recombinant vector comprising a recombinant avian adenovirus incorporating, and capable of expression of at least one heterologous nucleotide sequence. The nucleotide sequence is preferably one which encodes an antigenic determinate of infectious bursal disease virus. The invention further relates to a method of production of recombinant vectors, to methods of preparation of vaccines based on the vectors, to administration strategies and to methods of protecting poultry from disease.
Claims41
A recombinant avian adenovirus vector expressing at least one heterologous nucleotide sequence wherein the at least one heterologous nucleotide sequence is inserted into a non-essential region at the right hand end of the genome of the avian adenovirus between map units 60 and 100 and wherein the avian adenovirus excludes chicken embryo lethal orphan virus.
Dependencies are inferred from the claim text.