# US 6,296,834 B1 · Oral care composition

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- Number: US 6,296,834 B1
- Document ID: US6296834B1
- Status: Granted
- Kind: B1
- Application number: 09/552,071
- Filed: 2000-04-19
- Granted: 2001-10-02
- Earliest claimed: 1999-04-19
- Assignees: Unilever Home & Personal Care USA, Division of Conopco, Inc.
- Inventors: Laurence Marie Bernard; Alison Katharine Green; Elizabeth Sarah Mountney
- Web page: https://patentgrep.com/patent/US6296834B1

## CPC

- A61K 8/347: {Phenols}
- A61K 8/463: {containing sulfuric acid derivatives, e.g. sodium lauryl sulfate}
- A61K 8/55: Phosphorus compounds
- A61Q 11/00: Preparations for care of the teeth, of the oral cavity or of dentures; Dentifrices, e.g. toothpastes; Mouth rinses
- A61K: PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES (devices or methods specially adapted for bringing pharmaceutical products into particular physical or administering forms A61J3/00; chemical aspects of, or use of materials for deodorisation of air, for disinfection or sterilisation, or for bandages, dressings, absorbent pads or surgical articles A61L; soap compositions C11D)
- A61Q: SPECIFIC USE OF COSMETICS OR SIMILAR TOILETRY PREPARATIONS

## Abstract

The invention provides for an oral care composition which contains a non-cationic, water-insoluble or sparingly water-soluble antimicrobial agent, and an alkalimetal, ammonium or substituted ammonium alkylsulphate which contains a straight-chain, saturated or unsaturated C10 alkyl group. Such oral care composition provides for a higher antimicrobial efficacy than similar compositions which, however, contain predominantly an alkalimetal C12 alkylsulphate

## Claims

### Claim 1

An oral care composition comprising from about 0.1 to about 1% by weight of a non-cationic, water-insoluble or sparingly water-soluble antimicrobial agent, and a foaming effective amount of an alkali, ammonium or substituted ammonium C8-C18 alkylsulphate salt, wherein the C8-C18 alkylsulphate salt comprises at least 30% by weight of a straight-chain, saturated or unsaturated C10 alkyl group.

### Claim 2 (depends on 1)

A composition according to claim 1, wherein the C8-C18 alkylsulphate salt comprises at least 45% by weight of the straight-chain, saturated C10 alkyl group, the balance being a straight-chain, saturated predominantly C12 alkyl or higher group.

### Claim 3 (depends on 1)

A composition according to claim 1 characterised in that the antimicrobial agent is Triclosan.

### Claim 4 (depends on 1)

A composition according to claim 1 characterised in that it further comprises calcium glycerophosphate.

### Claim 5

An oral care composition comprising:
(i) from about 0.1 to about 1% by weight of a non-cationic, water-insoluble or sparingly water-soluble antimicrobial agent;
(ii) from about 0.5 to about 3% by weight of an alkalimetal, ammonium or substituted ammonium C8-C18 alkylsulphate detergent, wherein at least 30% by weight of the detergent is an alkalimetal, ammonium or substituted ammonium alkylsulphate with a straight-chain, saturated or unsaturated C10 alkyl group; and
(iii) a sodium or stannous fluoride present in an effective amount to prevent caries.

### Claim 6

A method for controlling microbial growth on a surface, comprising applying to the surface a composition comprising from about 0.1 to about 1% by weight of a non-cationic, water-insoluble or sparingly water-soluble antimicrobial agent, and a foaming effective amount of an alkali, ammonium or substituted ammonium C8-C18 alkylsulphate salt, wherein the C8-C18 alkylsulphate salt comprises at least 30% by weight of a straight-chain, saturated or unsaturated C10 alkyl group.