Isotopic urea tablets

A tablet containing isotope-labeled urea and an inorganic compound,

• wherein the tablet is formulated for detecting urease-producing microorganism in the stomach, and
• wherein said inorganic compound prevents stickiness of urea onto formulation machines during production of the tablet.

A tablet containing isotope-labeled urea and an inorganic compound,

• wherein the tablet is formulated for detecting the presence of urease-producing microorganism in the stomach,
• wherein said inorganic compound prevents cohesion of urea due to the stickiness of urea in the tablet, and stickiness of urea onto formulation machines during production of the tablet.

A tablet according to 4, wherein the organic compound is a sugar.

A method for detecting urease-producing microorganism in the stomach, comprising, administering a tablet containing isotope-labeled urea and an inorganic compound, and detecting the isotope-labeled carbon dioxide secreted via exhaled air.

A process for producing a tablet containing isotope-labeled urea which is used for detecting urease-producing microorganism, comprising,

• mixing an inorganic compound with the isotope-labeled urea to give a mixture, and
• formulating the mixture into a tablet with a formulation machine.

A process for producing a tablet containing isotope-labeled urea which is used for detecting urease-producing microorganism, comprising,

• mixing an inorganic compound with the isotope-labeled urea to give a mixture,
• grinding the mixture with grinder to give ground product, and
• formulating the ground product into a tablet with a formulation machine.

A tablet containing isotope-labeled urea and an inorganic compound obtainable by mixing the inorganic compound with the isotope-labeled urea to give a mixture, grinding the mixture with a grinder to give ground product, and formulating the ground product into a tablet with a formulation machine,

• wherein the tablet is formulated for detecting urease-producing microorganism in the stomach.

A tablet containing isotope-labeled urea and an inorganic compound, obtainable by mixing the inorganic compound with the isotope-labeled urea to give a mixture, grinding the mixture with a grinder to give ground product, and formulating the ground product into a tablet with a formulation machine,

• wherein the particle size of the ground product is 100 μm or less, and the tablet is for detecting urease-producing microorganism in the stomach.

As. A tablet according to 28, wherein the organic compound is a sugar.

A tablet containing isotope-labeled urea and an inorganic compound.