Mammalian cell cycle protein
AssigneesAmgen Inc., The Regents of the University of California
InventorJasminder Weinstein
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Abstract
A novel mammalian cell cycle protein, p55CDC, DNA sequences encoding p55CDC, and a method for producing the protein are described. Also described are methods for detecting p55CDC and methods for modulating cell division by compounds which control the level or activity of p55CDC or p55CDC-associated protein complexes.
Claims7
An isolated mammalian p55CDC polypeptide capable of forming a complex having cell cycle dependent kinase activity against at least histone H1, alpha-casein, and myelin basic protein comprising the amino acid sequence of SEQ ID NO:
- 4 or a biologically active fragment thereof.
An isolated mammalian p55CDC polypeptide capable of forming a complex having cell cycle dependent kinase activity against at least histone H1, alpha-casein, and myelin basic protein comprising the amino acid sequence of SEQ ID NO:2 or a biologically active fragment thereof.
Dependencies are inferred from the claim text.