Enzyme-containing polymeric sensors
AssigneeAgentase, LLC
InventorsKeith E. LeJeune, Alan J. Russell
Life of this patent
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Abstract
A sensor for detecting the presence of at least one analyte includes at least one enzyme that is selected to either (i) catalyze a reaction of the analyte to chemically convert the analyte to a product compound or (ii) be inhibited by the analyte in the presence of a substrate compound. The sensor also includes at least one indicator compound selected to produce a measurable change of state as a result of the interaction of the analyte and the enzyme. Each of the enzyme and the indicator compound are incorporated within a single polymer.
Claims15
A sensor for detecting the presence of at least one analyte in an environment, the sensor comprising:
- at least one enzyme that is selected (i) to catalyze a reaction of the analyte to chemically convert the analyte to a product compound or (ii) to be inhibited by the analyte in the presence of a substrate compound;
- and
- at least one indicator compound selected to produce a measurable change of state as a result of the interaction of the analyte and the enzyme;
- each of the enzyme and the indicator compound being incorporated within a single polymer.
A process for preparing a sensor to detect the presence of at least one analyte comprising the steps of:
- incorporating at least one enzyme that is selected (i) to catalyze a reaction of the analyte to chemically convert the analyte to a product compound or (ii) to be inhibited by the analyte in the presence of a substrate compound into a polymer;
- and
- incorporating at least one indicator compound selected to produce a measurable change of state as a result of the interaction of the analyte and the enzyme into the polymer.
A method for detecting the presence of at least one analyte, the method comprising the steps of:
- exposing a sensor to an environment in which the analyte is present, the sensor including at least one enzyme that is selected (i) to catalyze a reaction of the analyte to chemically convert the analyte to a product compound or (ii) to be inhibited by the analyte in the presence of a substrate compound, the sensor further including at least one indicator compound selected to produce a measurable change of state as a result of the interaction of the analyte and the enzyme, each of the enzyme and the indicator compound being incorporated within a single polymer;
- and
- measuring the change of state.
Dependencies are inferred from the claim text.