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US 6,287,765 B1Granted
Methods for detecting and identifying single molecules
AssigneeMolecular Machines, Inc.
InventorRoger S. Cubicciotti
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AssigneeMolecular Machines, Inc.
InventorRoger S. Cubicciotti
Estimating the term…
Multimolecular devices and drug delivery systems prepared from synthetic heteropolymers, heteropolymeric discrete structures, multivalent heteropolymeric hybrid structures, aptameric multimolecular devices, multivalent imprints, tethered specific recognition devices, paired specific recognition devices, nonaptameric multimolecular devices and immobilized multimolecular structures are provided, including molecular adsorbents and multimolecular adherents, adhesives, transducers, switches, sensors and delivery systems. Methods for selecting single synthetic nucleotides, shape-specific probes and specifically attractive surfaces for use in these multimolecular devices are also provided. In addition, paired nucleotide-nonnucleotide mapping libraries for transposition of selected populations of selected nonoligonucleotide molecules into selected populations of replicatable nucleotide sequences are described.
A method of detecting a single nonnaturally occurring oligonucleotide molecule capable of specifically binding to a selected nonoligonucleotide molecule comprising:
A method of detecting a single nonnaturally occurring oligonucleotide molecule capable of specifically binding to a selected nonoligonucleotide molecule comprising:
A method of detecting a single nonnaturally occurring oligonucleotide molecule capable of specifically binding to a selected target that is not a DNA-binding protein comprising:
A method of detecting a single nonnaturally occurring oligonucleotide conjugate molecule capable of specifically binding to a selected nonoligonucleotide molecule, said method comprising:
A method of detecting a single nonoligonucleotide molecule comprising:
Dependencies are inferred from the claim text.