Muscle contraction assist device
AssigneeImpulse Dynamics N. V.
InventorsShlomo Ben-Haim, Nissim Darvish, Yuval Mika, Benny Rousso, Bella Felzen
Life of this patent
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Abstract
A method and apparatus for controlling a segment of excitable tissue, typically tissue of a heart, the segment having an intrinsic activity level. During a high phase, electrical energy of a given amplitude is applied to the segment. During a low phase, the amplitude of the electrical energy applied to the segment is reduced relative to that applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level.
Claims17
A method for controlling a segment of excitable muscle tissue, the segment having an intrinsic activity level, at which intrinsic activity level the segment generates a first force of contraction, the method comprising:
- during a high phase, applying electrical energy of a given amplitude to the segment;
- and
- during a low phase, reducing the amplitude of the electrical energy applied to the segment relative to that applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level, and causes a second force to be generated in the segment that is greater than the first force.
A method for controlling a segment of excitable muscle tissue of a heart having a cardiac output caused by a first force of contraction of the segment at an intrinsic activity level thereof, the method comprising:
- during a high phase, applying electrical energy of a given amplitude to the segment;
- and
- during a low phase, reducing the amplitude of the electrical energy applied to the segment relative to that applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level, and causes a second force to be generated in the segment that is greater than the first force, such that the cardiac output increases as a result of the segment generating the second force.
A method for controlling a segment of excitable muscle tissue of a heart having an intrinsic activity level, at which intrinsic activity level the segment generates a first force of contraction, the method comprising:
- during a high phase, applying electrical energy of a given amplitude to the segment;
- and
- during a low phase, reducing the amplitude of the electrical energy applied to the segment relative to that applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level, and causes a second force to be generated in the segment that is greater than the first force, such that blood pressure generated by the heart increases as a result of the segment generating the second force.
A method for controlling a segment of excitable tissue, the segment having an intrinsic activity level, the method comprising:
- during a high phase, injecting current into the segment at a generally constant rate which is below a threshold for inducing a contraction of muscle tissue of the segment, so as to generate an electric field in the segment which substantially does not cause contraction of the muscle tissue;
- and
- during a low phase, reducing the rate of injection of the current relative to the rate of injection during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level.
A method for controlling a plurality of segments of excitable tissue of a heart, each segment having a respective intrinsic activity level, the method comprising:
- during respective high phases, applying electrical energy of respective given amplitudes to the plurality of segments;
- and
- during respective low phases, reducing the amplitude of the electrical energy applied to each of the segments, so that the activity levels of the segments increase during the respective low phases above their respective intrinsic activity levels.
A method for controlling a segment of excitable tissue, the segment having an intrinsic activity level, the method comprising:
- during a high phase, applying energy of a given amplitude to the segment for a substantially continuous period longer than 10 seconds;
- and
- during a low phase, reducing the amplitude of the electrical energy applied to the segment relative to that applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level.
A method for controlling a segment of excitable tissue, the segment having an intrinsic activity level, the method comprising:
- during a high phase, applying electrical energy of a given amplitude to the segment;
- and
- during a low phase, extending for a substantially continuous period longer than 10 seconds, reducing the amplitude of the electrical energy applied to the segment relative to that applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level.
A method for controlling a segment of excitable tissue of a heart, the segment having an intrinsic activity level, the method comprising:
- during a high phase, applying electrical energy of a given amplitude to the segment;
- during a low phase, reducing the amplitude of the electrical energy applied to the segment relative to that applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level;
- sensing motion of a portion of the heart;
- and
- modifying, responsive to the sensing, a characteristic of the application of the electrical energy.
A method for controlling a segment of excitable tissue, the segment having an intrinsic activity level, the method comprising:
- during a high phase, applying electrical energy of a given amplitude to the segment;
- and
- during a low phase, reducing the amplitude of the electrical energy applied to the segment relative to that applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level, such that an average activity level of the segment over a period of at least one minute including the high and low phases is substantially greater than the intrinsic activity level.
Apparatus for controlling a segment of excitable muscle tissue, the segment having an intrinsic activity level, at which intrinsic activity level the segment generates a first force of contraction, the apparatus comprising:
- one or more electrodes, adapted to be coupled to the segment;
- and
- a control unit, adapted to actuate the electrodes to apply electrical energy of a given amplitude to the segment during a high phase, which is followed by a low phase, during which low phase the control unit is adapted to reduce the amplitude of the electrical energy applied to the segment relative to the energy applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level and a second force is generated in the segment that is greater than the first force.
Apparatus for controlling a plurality of segments of excitable tissue of a heart, each segment having a respective intrinsic activity level, the apparatus comprising:
- a plurality of electrodes, adapted to be coupled respectively to the plurality of segments;
- and
- a control unit, adapted to actuate the electrodes to apply electrical energy of respective given amplitudes to the segments in respective high phases, and to reduce the respective amplitudes of the energy applied to the segments during respective low phases, so as to increase the activity levels of the segments above their respective intrinsic activity levels.
Apparatus for controlling a segment of excitable tissue of a patient, the segment having an intrinsic activity level, the apparatus comprising:
- one or more electrodes, adapted to be coupled to the segment;
- and
- a control unit, adapted to actuate the electrodes to apply electrical energy of a given amplitude to the segment during a high phase, which is followed by a low phase, during which low phase the control unit is adapted to reduce the amplitude of the electrical energy applied to the segment relative to the energy applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level, and such that an average activity level of the segment over a period of at least one minute including the high and low phases is substantially greater than the intrinsic activity level.
Apparatus for controlling a segment of excitable tissue of a patient, the segment having an intrinsic activity level, the apparatus comprising:
- one or more electrodes, adapted to be coupled to the segment;
- and
- a control unit comprising a console external to the body of the patient, the control unit being adapted to actuate the electrodes to apply electrical energy of a given amplitude to the segment during a high phase, which is followed by a low phase, during which low phase the control unit is adapted to reduce the amplitude of the electrical energy applied to the segment relative to the energy applied during the high phase, so that the segment's activity level increases during the low phase above the intrinsic activity level.
Dependencies are inferred from the claim text.