Process for preparing (1→3)-β-D-glucan from fungi
AssigneeSeikagaku Corporation
InventorsHiroshi Tamura, Maki Aizawa, Shigenori Tanaka
Life of this patent
Estimating the term…
Abstract
The present invention relates to a process for preparing (1→3)-β-D-glucan, comprising subjecting a fungal cell to oxidation degradation under alkaline conditions to release (1→3)-β-D-glucan from a cell wall of the cell. (1→3)-β-D-Glucan can be prepared easily and efficiently from a cell of a microorganism belonging to the genus Candida. An accurate measurement process having a high reproducibility of (1→3)-β-D-glucan can be provided by using the above-described glucan or stabilized glucan into a kit and using it as a standard substance, and a large amount of the (1→3)-β-D-glucan having various biological activities can be solubilized and purified from a fungus, such as Candida or the like.
Claims11
A process for preparing (1→3)-β-D-glucan, comprising subjecting a fungal cell to oxidation degradation under alkaline conditions and dissolving a water-insoluble fraction obtained by the oxidation degradation in an aprotic polar solvent.
(1→3)-β-D-Glucan soluble in an aprotic polar solvent, which is obtainable by subjecting a cell of a microorganism belonging to the genus Candida to oxidation degradation under alkaline conditions to release (1→3)-β-D-glucan from a cell wall of the cell.
The (1→3)-β-D-glucan composition according to claim 11, which is a freeze-dried product.
Dependencies are inferred from the claim text.