1-arenesulfonyl-2-aryl-pyrrolidine and pyridine derivatives

A compound of formula I:

• wherein
• R1 signifies hydrogen, lower alkyl or hydroxy-lower alkyl;
• R2 signifies furyl, thienyl, pyridyl or phenyl, which is optionally substituted by 1 to 3 substituents, selected from lower alkyl, lower alkoxy, halogen, cyano, CF3 or —N(R4)2;
• R3 signifies naphthyl or phenyl, which is optionally substituted by 1 to 3 substituents, selected from lower alkyl, lower alkoxy, halogen, acetyl, cyano, hydroxy-lower alkyl, —CH2-morpholin-4-yl, lower alkyl-oxy-lower alkyl, lower alkyl-N(R4)2 or CF3;
• R4 signifies, independently from each other, hydrogen or lower alkyl,
• as well as their pharmaceutically acceptable salts, with the exception of
• (RS)-2-phenyl-1-(toluene-4-sulfonyl)-pyrrolidine;
• and,
• (RS)-1-(toluene-4-sulfonyl)-2-p-tolyl-pyrrolidine as well as their pharmaceutically acceptable salts.