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US 6,284,495 B1Granted
Method for producing nucleic acid substances
AssigneeAjinomoto Co., Inc.
InventorsKatsuaki Sato, Yoshihiro Usuda
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Abstract
A nucleic acid substance is efficiently produced by cultivating a microorganism whose repressor protein for purine operon does not function in a normal manner, preferably a strain whose gene encoding the repressor protein on a chromosome (purR) is disrupted, in a culture medium so that the nucleic acid substance should accumulate in the culture medium, and collecting the substance from the culture medium.
Claims7
A method for producing a nucleic acid substance comprising steps of:
- cultivating in a culture medium a microorganism whose repressor protein for purine operon does not function in a normal manner to produce and accumulate the nucleic acid substance in the culture medium, and
- collecting the substance from the culture medium.
Dependencies are inferred from the claim text.