Treatment of herpes infection with composition containing quaternary ammonium compound and an anti-viral agent
AssigneeBio Pharma Sciences B.V.
InventorDirk Andre Richard Van den Berghe
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Abstract
A pharmaceutical composition and method for the treatment of herpes simplex infections is disclosed. The composition contains a quaternary ammonium compound such as cetrimide or benzalkonium chloride and an antiviral agent such as acyclovir, bromoinyldesoxuridine, 3-fluorothymidine, idoxuridine, propyl gallate, proanthocyanides or glucosamine. The compound can also contain a plant extract such as camomile.
Claims10
A pharmaceutical composition for the treatment of herpes simplex infections, comprising a quaternary ammonium compound in a concentration effective to exhibit virucidal activity against herpes simplex virus, an antiviral agent and a pharmaceutically acceptable base, wherein the quaternary ammonium compound is present in a range from about 0.1% to about 5% and is selected from the group consisting of cetrimide and a benzalkonium compound;
- and the antiviral agent is present in a range from about 0.01% to about 3% and is selected from the group consisting of an acyclovir, bromylvinyldesoxuridine, 3-fluorothymidine, idoxuridine, propyl gallate, ethyl gallate, proanthocyanides and glucosamine, wherein the quaternary ammonium compound and the antiviral agent are mutually compatible.
A pharmaceutical composition for the treatment of herpes simplex virus infections, comprising:
- PEG 400 52% PEG 4000 26% glycerol 9% cetrimide 1% choline (optional) 2% cetyl alcohol 1% camomile extract 8% propyl gallate 0.25%
A method for the treatment of herpes simplex infections, comprising administration of a pharmaceutical composition comprising a quaternary ammonium compound in a concentration effective to exhibit virucidal activity against herpes simplex virus, an antiviral agent, and a pharmaceutically acceptable base, wherein the quaternary ammonium compound and the antiviral agent are mutually compatible, the quaternary ammonium compound is present in a range about 0.1 to about 5% and is selected from the group consisting of cetrimide and a benzalkonium compound, the antiviral agent is present in a range from about 0.01 to about 3% and is selected from the group consisting of an acyclovir, bromoinyldesoxuridine, 3-fluorothymidine, idoxuridine, propyl gallate, ethyl gallate, proanthocyanides and glucosamine.
Dependencies are inferred from the claim text.