Pharmaceutical compositions containing an effervescent acid-base couple
AssigneeChiesi Farmaceutici S.p.A.
InventorsPaolo Chiesi, Paolo Ventura, Rosa Mezzadri, Gaetano Brambilla, Daniela Acerbi
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Abstract
A pharmaceutical composition in the form of effervescent tablets comprising an active ingredient and an effervescent blend, wherein the effervescent blend comprises an acidic component and sodium glycine carbonate as alkaline components. Preferred acid components are fumaric acid, maleic acid, and their salts. Tablets are prepared in normal thermo-hygrometric conditions and with standard tabletting equipment.
Claims4
A pharmaceutical composition in form of an effervescent or fast-dissolving, the couple tablet comprising an active ingredient and an effervescent couple comprising an acidic component and an alkaline component, wherein the active ingredient is a combination of levodopa methyl ester and carbidopa, the acidic component is selected from fumaric acid, maleic acid or their salts and the alkaline component is sodium glycine carbonate.
Dependencies are inferred from the claim text.