Compounds and methods for treatment and diagnosis of mycobacterial infections
AssigneeGenesis Research & Development Corporation Limited
InventorsPaul Tan, Jun Hiyama, Elizabeth Visser, Linda Scott
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Abstract
The present invention provides polypeptides comprising an immunogenic portion of a M. vaccae soluble protein and DNA molecules encoding such polypeptides, together with methods for their use in the diagnosis and treatment of mycobacterial infection. Methods for enhancing the immune response to an antigen including administration of M. vaccae culture filtrate or delipidated M. vaccae cells are also provided.
Claims19
An isolated polypeptide comprising SEQ ID NO:44.
A fusion protein comprising at least two polypeptides, wherein at least one of the polypeptides comprises SEQ ID NO:44.
A composition comprising a polypeptide and a non-specific immune response amplifier, wherein the polypeptide comprises SEQ ID NO:44.
Dependencies are inferred from the claim text.