Cell lines infected with granulocytic ehrlichia, vaccines, diagnostics and methods
AssigneeAquila Biopharmaceuticals, Inc.
InventorsRichard T. Coughlin, Cindy Gingrich-Baker
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Abstract
The present invention relates, in general, to granulocytic Ehrlichia. In particular, the present invention relates to a human promyelocytic leukemia cell line infected with granulocytic Ehrlichia, a method of continually growing granulocytic Ehrlichia, vaccines comprising granulocytic Ehrlichia or granulocytic Ehrlichia antigens, methods of preventing ehrlichiosis in an animal, antibodies to granulocytic Ehrlichia, and methods for identifying granulocytic Ehrlichia in an animal.
Claims6
A composition comprising granulocytic Ehrlichia together with a pharmaceutically acceptable diluent, carrier, or excipient, wherein said granulocytic Ehrlichia is present in an amount effective to elicit an immune response in an animal to granulocytic Ehrlichia, and wherein said granulocytic Ehrlichia is isolated from a cultured cell line infected with human granulocytic Ehrlichia, E. equi, or E. phagocytophila.
A composition comprising a granulocytic Ehrlichia antigen together with a pharmaceutically acceptable diluent, carrier, or excipient, wherein said antigen is present in an amount effective to elicit immune responses in an animal to granulocytic Ehrlichia, and wherein said antigen is isolated from a cultured cell line infected with human granulocytic Ehrlichia, E. equi, or E. phagocytophila.
Dependencies are inferred from the claim text.