Methods of treatment using IL-6
OwnerSteven C. Clark, Gordon G. Wong +2inventors
InventorsSteven C. Clark, Gordon G. Wong, Paul Schendel, John McCoy
Life of this patent
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Abstract
IL-6 is produced via recombinant DNA techniques. The peptide is useful in the treatment of disorders characterized by deficiencies in hematopoietic cells and in combination with other hematopoietins in cancer therapies.
Claims8
A method for stimulating growth of hematopoietic cells in a patient suffering from an immune system deficiency resulting from exposure to radiation, which comprises administering an effective amount of a protein selected from the group consisting of a protein having the amino acid sequence set forth in FIG. 1, said protein being produced in mammalian cells containing the DNA sequence set forth in FIG. 1;
- a protein having the amino acid sequence set forth in FIG. 1 from amino acid 28 to amino acid 212;
- and a non-glycosylated protein having the amino acid sequence set forth in FIG. 2 from amino acid 29 to amino acid 212.
A method for stimulating growth of hematopoietic cells in a patient suffering from an immune system deficiency resulting from exposure to chemotherapy, which comprises administering an effective amount of a protein selected from the group consisting of a protein having the amino acid sequence set forth in FIG. 1, said protein being produced in mammalian cells containing the DNA sequence set forth in FIG. 1;
- a protein having the amino acid sequence set forth in FIG. 1 from amino acid 28 to amino acid 212;
- and a non-glycosylated protein having the amino acid sequence set forth in FIG. 2 from amino acid 29 to amino acid 212.
Dependencies are inferred from the claim text.