Non-invasive composition analysis
AssigneeQuanta Vision, Inc.
InventorsPavel Lazarev, Mikhail Paukshto
Life of this patent
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Abstract
A method for characterizing a test sample of biological tissue is disclosed. The method includes obtaining a radiation scattering pattern produced by the test sample of biological tissue and processing the radiation scattering pattern to determine a pair distance distribution function for the test sample. The method also includes comparing sample data derived from the pair distance distribution function with known data derived from known samples which each have one or more known characteristics.
Claims28
A method for analyzing a characteristic of a test sample of biological tissue, comprising:
- obtaining a radiation scattering pattern produced by the test sample of biological tissue;
- processing the radiation scattering pattern to determine a pair distance distribution function for the test sample;
- and
- comparing the test sample pair distance distribution function with pair distance distribution functions of control samples of biological tissue which each have a known property with regard to the characteristic being analyzed the comparison being performed where the control pair distance distribution functions are sensitive to change in relation to the characteristic being analyzed.
A method for characterizing a test sample of biological tissue, comprising:
- obtaining a radiation scattering pattern produced by the test sample of biological tissue;
- processing the radiation scattering pattern to determine a pair distance distribution function for the test sample;
- and
- comparing sample data derived from the pair distance distribution function with known data derived from known samples which each have one or more known characteristics;
- wherein the known data is a relationship between the value of the characteristic and a value of the pair distance distribution function at a particular pair distance.
A method for characterizing a test sample of biological tissue, comprising:
- obtaining a radiation scattering pattern produced by the test sample of biological tissue;
- processing the radiation scattering pattern to determine a pair distance distribution function for the test sample;
- and
- comparing sample data derived from the pair distance distribution function with known data derived from known samples which each have one or more known characteristics, wherein the known data is subdivided into known data sets, each known data set being associated with a particular class of known sample, and wherein comparing the sample data comprising
- identifying a value of the pair distance distribution function at one or more sensitive pair distances where a value of the pair distance distribution function is sensitive to changes in the value of the characteristic, each sensitive pair distance being associated with a particular class of known sample;
- providing a mathematical relationships between the value of the characteristic and the value of the pair distance distribution function at each of the one or more sensitive pair distances,
- substituting each identified value into the mathematical relationship associated with the same sensitive pair distance as the identified value, the substitutions yielding a plurality of potential approximate characteristic values which are each associated with a class of known samples,
- finding the deviation among the potential approximate characteristic values associated with a particular class of known samples for each class of known samples,
- identifying the class of known samples associated with the lowest deviation;
- and
- characterizing the test sample as belonging to the identified class.
A computer readable medium which has stored thereon computer executable logic which, when executed by a processor, causes processor to perform the acts of:
- processing data regarding a radiation scattering pattern obtained from a test sample of biological material to determine a pair distance distribution function for the test sample;
- and
- comparing the test sample pair distance distribution function with pair distance distribution functions of control samples of biological tissue which each have a known property with regard to the characteristic being analyzed, the comparison being performed where the control pair distance distribution functions are sensitive to change in relation to the characteristic being analyzed.
A computer readable medium which has stored thereon computer executable logic which, when executed bv a processor, causes the processor to perform the acts of:
- processing data regarding a radiation scattering pattern obtained from a test sample of biological material to determine a pair distance distribution function for the test sample;
- and
- comparing the test sample pair distance distribution function with pair distance distribution functions of control samples of different classes of biological tissue, the comparisons being performed for each class where the control pair distance distribution function for that class is sensitive to chance in relation to that characteristic,
- determining the class to which the test sample belongs by identifying which class the test sample best matches based on the comparisons between the test sample pair distance distribution function and the control pair distance distribution functions for the different classes of biological tissue.
Dependencies are inferred from the claim text.