Pharmaceutical composition with sotalol combination and their use in treatment of cardiac ailments
AssigneeTorrent Pharmaceutical Ltd.
InventorAlangudi Sankaranarayanan
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Abstract
The invention discloses a safer Antiarrhythmic drug with controlled Beta Adrenergic activity which comprises a combination of dextro- and laevo-rotatory isomers of sotalol as active ingredients, pharmaceutical compositions with said combination as active ingredients and its preparation and use of the said combination in the treatment of cardiac ailments in mammals including human beings.
Claims15
A method of treatment of cardiac ailment in mammals including human beings, which comprises, administering to a mammal in need thereof, an optimally effective amount of a combination of dextro- and laevo-isomers of sotalol or their pharmaceutically acceptable salts wherein the ratio of dextro- and laevo-isomers of sotalol is 1.5:1 to 3.5:1.
A pharmaceutical composition for use as an antiarrhythmic drug with controlled beta adrenergic blockade which comprises a combination of dextro- and laevo-rotatory isomers of sotalol or their pharmaceutically acceptable salts as active ingredients wherein the range of ratio of dextro- and laevo-isomers in the said combination is 1.50:1 to 3.5:1.
Dependencies are inferred from the claim text.