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US 6,281,225 B1Granted
Inhibiting proliferation of arterial smooth muscle cells
AssigneeCerus Corporation
InventorsJohn E. Hearst, William M. Greenman, Susan Wollowitz, Ryan D. Alfonso
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Abstract
The present invention provides methods for inhibiting restenosis at a site of vascular recanalization. The methods include intravascular administration of a reactive acridine compound to the site of injury, without the requirement for activation or sustained release of the compound.
Claims11
A method for inhibiting restenosis, the method comprising local administration of an alkylating compound to a site of vascular recanalization, wherein said alkylating
- compound is selected from the group consisting of:
- and all salts thereof.
Dependencies are inferred from the claim text.