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US 6,281,219 B1Granted
Acaricidal and insecticidal substituted pyrimidines and a process for the preparation thereof
AssigneeAmerican Cyanamid Company
InventorsSalvatore John Cuccia, William Wakefield Wood, Brian Lee Buckwalter, John Francis Chiarello, Linda Barbara Fleming
Life of this patent
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Abstract
The present invention provides compounds of Formula I methods for their preparation and their use as acaricidal and insecticidal agents.
Claims16
A compound of Formula I
- wherein
- R1 is hydrogen, (C1-6)alkylthio, halo(C1-6)alkylthio (C1-6)alkylsulphinyl, halo(C1-6)alkylsulphinyl, (C1-6)alkylsulphonyl, halo(C1-6)alkylsulphonyl or NR12R13;
- R12 and R13 are each independently hydrogen,(C1-6)alkyl, or halo(C1-6)alkyl;
- R2, R3, R4, R5, R6, R7, R8, R9 and R11 are each independently selected from hydrogen, halogen, cyano, nitro, (C1-6)alkyl, halo(C1-6)alkyl, (C1-6)alkoxy, halo(C1-6)alkoxy, (C1-6)alkoxy(C1-6)alkyl, halo(C1-6)alkoxy(C1-6)alkyl, (C1-6)alkylthio, halo(C1-6)alkylthio, (C1-6)alkyl sulphinyl, halo(C1-6)alkylsulphinyl, (C1-6)alkylsulphonyl, halo(C1-6)alkylsulphonyl, amino, (C1-6)alkylamino, di(C1-6)alkylamino, halo(C1-6)alkylamino,(C1-6)alkylhaloalkyl(C1-6amino, dihalo(C1-6)alkylamino, (C1-6)alkyloxy-carbonyl, halo(C1-6)alkyloxycarbonyl, (C2-6)alkenyl, halo(C2-6)alkenyl, (C2-6)alkynyl, halo(C2-6)alkynyl;
- R10 is halogen, halo(C1-6)alkyl, halo(C2-6)alkenyl or halo(C2-6)alkynyl;
- and X1 and X2 are independently selected from the group consisting of NR14, NR15, O, CH2, CR18R19, CO, C═NOR20;
- wherein R14 is (C1-6)alkyl;
- R15 is H, (C1-6)alkyl or CH(OR16)(OR17);
- R16 and R17 are each independently (C1-6)alkyl;
- R18 and R19 each independently selected from H, (C1-6)alkyl, (C2-6)alkenyl and (C2-6)alkynyl which are all optionally substituted by one or more halogens which are the same or different, or R18 and R19 may together form a carbocyclic ring which is optionally substituted by one or more halogens which are the same or different;
- R20 is (C1-6)alkyl;
- with the proviso that X1 cannot be the same as X2, and with the proviso that the compound of formula 1 is not 4-[m-(trifluoromethyl)benzyl]-]6-(α,α,α-trifluoro-N-methyl-m-toluidino)pyrimidine.
9 more elements
Dependencies are inferred from the claim text.