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US 6,281,201 B1Granted
Base-modified derivatives of 2′,5′-oligoadenylate and antiviral uses thereof
AssigneeTemple University of the Commonwealth System of Higher Education
InventorsRobert J. Suhadolnik, Wolfgang Pfleiderer
Life of this patent
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Abstract
Antiviral compounds have the formula wherein m is zero, 1, 2 or 3; n is from 1 to 8, preferably 1, 2 or 3; most preferably 1 or 2; R is independently selected from the group consisting of provided that all R may not be R1 is independently selected from the group consisting of hydroxyl and hydrogen; R2 is independently selected from the group consisting of oxygen and sulfur; or water soluble salts thereof.
Claims20
A compound of the formula:
- wherein
- m is zero, 1, 2 or 3;
- n is from 1 to 8;
- R is independently selected from the group consisting of
- provided that all R may not be
- R1 is independently selected from the group consisting of hydroxyl and hydrogen;
- R2 is independently selected from the group consisting of oxygen and sulfur;
- or water-soluble salt of said compound.
5 more elements
A compound according to clain 6 wherein each R is selected from the group consisting of
Dependencies are inferred from the claim text.