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US 6,281,012 B1Granted
Method of preparing suppressor T cells with allogeneic mesenchymal stem cells
AssigneeOsiris Therapeutics, Inc.
InventorsKevin McIntosh, Elena Klyushnenkova
Life of this patent
Estimating the term…
Abstract
A method of reducing an immune response to a transplant in a recipient by treating said recipient with an amount of suppressor T cells effective to reduce or inhibit host rejection of the transplant. The suppressor T cells can be administered before, at the same time as, or after the transplant. Also disclosed is a method of inducing a reduced immune response against a host by foreign tissue, i.e., graft versus host disease, by treatment with suppressor T cells.
Claims2
A method of preparing suppressor T-cells, comprising:
- contacting activated immune effector T-Cells with allogeneic mesenchymal stem cells in culture to produce suppressor T-cells;
- and
- separating said suppressor T-cells from said culture.
Dependencies are inferred from the claim text.